Chemosensitivity Test

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منابع مشابه

[In vitro chemosensitivity test by human tumor colony forming assay].

In vitro chemosensitivity of urological cancers was assessed by a human tumor colony forming assay (HTCA) and a 3H-thymidine incorporation assay. Primary tumor cells from 160 of 253 (63%) urological cancers showed adequate colony growth (greater than 30 colonies per well), and there was a 57% true positive and 100% true negative rate for predicting clinical response of anticancer agents. On the...

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Effective chemotherapy based on a chemosensitivity test for malignant pleural mesothelioma.

Malignant pleural mesothelioma (MPM) is an aggressive and fatal tumor of the pleura and its incidence has been increasing as a result of the widespread use of asbestos worldwide. Numerous chemotherapeutic agents have been tested in many clinical trials, but the response rate does not exceed 20% for most of the investigated regimens. Here we report a case of MPM in which the chemotherapy based o...

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[Efficacy of the chemosensitivity test using collagen gel matrix-supported culture system for urogenital tumors].

BACKGROUND We evaluated the usefulness of in vitro tumor culture system using a specialized collagen gel matrix (CGM assay) as a chemosensitivity test. PATIENTS AND METHODS Chemosensitivity results of CGM assay were compared with other in vivo and in vitro assays on an implantable murine bladder tumor cell line (MBT-2). In addition we investigated the possibility of the clinical use of CGM as...

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Individualized adjuvant chemotherapy guided by chemosensitivity test sequential to extended surgery for advanced gastric cancer.

BACKGROUND AND OBJECTIVES Various adjuvant chemotherapy regimens have been proposed for patients with advanced gastric cancer; however, the majority of these trials failed to show a clear survival benefit over surgery alone. In this study, the feasibility and efficacy of a strategy of extended surgery combined with individualized adjuvant chemotherapy for advanced gastric cancer with serosal in...

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Peripheral Chemosensitivity Assessed by the Modified Transient 02 Test in Female

To evaluate genetic influence on the control of breathing in adult men, we measured, in healthy female twins, ventilatory responses to isocapnic progressive hypoxia and hyperoxic progressive hypercapnia, and the withdrawal response(the modified transient 0,, test)which is considered to selectively reflect peripheral chemoreceptor activity. The withdrawal response was Obtained as the magnitude o...

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ژورنال

عنوان ژورنال: Journal of Experimental and Basic Medical Sciences

سال: 2020

ISSN: 2717-9478

DOI: 10.5606/jebms.2020.75619